We have an unparalleled depth and breath of biotechnology experience, in all major disciplines and practice areas. Our leading edge capabilities encompass Genetics, Computer Science, Clinical Medicine, Engineering, Epidemiology, Information Technology, Molecular Biology and Biostatistics.

Diagnostics and Risk Profiling: Predicting Disease

Diagnostics is one of the fastest growing branches of modern day genomics. Combining modern knowledge of the human genome and proteome with state of the art information technology, diagnostics seeks to allow the prediction of genetic susceptibility and onset timing of disease.

Common human diseases that are the subject of such research efforts include asthma, heart disease, leukemia, juvenile diabetes, mental illness, alcoholism, Alzheimer's disease, and various cancers. The early detection of complex diseases through genetic testing will allow the development of proactive, prophylactic therapies that promise to increase disease survivability dramatically.

Triaj offers expertise at the highest levels in a broad range of services related to diagnostics, from general advisory and project review to large scale applied consulting projects. Triaj's biotechnology professionals are recognized international leaders in their fields, and include experts in genetics, genomics, proteomics, molecular biology, genetic statistics, clinical epidemiology, genetic epidemiology, biostatistics, bioinfomatics, diagnostics, therapeutics, and gene mapping.

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Proteomics: New Frontiers

Proteomics is the direct study of the proteins produced by genes and an alternative and complementary approach to genomic-based investigations. Proteomics aims to identify and validate the proteins that drive core biological functions, and describe changes in protein expression under the influence of disease or pharmacotherapy. High-throughput proteomic technologies are still in the early phases of development. Analogous to microarrays for functional gene expression analyses, such approaches have great potential to be used in developing new pharmacotherapies and other targeted therapies.

The market for all drug therapies is currently $400 billion, and is expected to grow to a multi-trillion dollar market, of which a great proportion will be protein based therapies. Triaj offers a comprehensive range of services related to proteomics, ranging from general advisory and project review to large scale applied consulting projects. Triaj's biotechnology professionals are recognized international leaders in their fields, and include experts in genetics, genomics, proteomics, molecular biology, genetic statistics, clinical epidemiology, genetic epidemiology, biostatistics, bioinfomatics, diagnostics, therapeutics, and gene mapping.

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Pharmacogenomics: Targeted therapies

Pharmacogenomics seeks to understand the genetic factors contributing to individual response to pharmacotherapy, and is currently one of the most active research areas in complex human disease genetic research. Over 100 drugs, targeting approximately 500 genes, have already been developed and approved in the United States or other countries as a result of pharmacogenetic research. Many hundreds more drugs, vaccines and diagnostic products are in advanced human clinical trials. Over 10,000 therapeutically significant genetic targets in humans are possible in the near future. These new targets will allow the development of new diagnostics, treatments and cures for disease and disease susceptibility and present an enormous commercial opportunity.

Triaj offers a broad range of services related to pharmacogenomics, ranging from general advisory and project review to large scale applied consulting projects. Triaj's biotechnology professionals are recognized international leaders in their fields, and include experts in genetics, genomics, proteomics, molecular biology, genetic statistics, clinical epidemiology, genetic epidemiology, biostatistics, bioinfomatics, diagnostics, therapeutics, and gene mapping. Triaj's professional staff has an unparalleled wealth of expertise in all aspects of pharmacogenomics, including study design, gene expression and microarray analysis, generation of molecular data, and biostatistical analysis.

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Gene Mapping: Identifying the Genes

The sequencing of the entire human genome, which is being vigorously pursued both by government and industry, is providing a wealth of new information as to genetic structure and diversity. The construction of genetic maps, together with sophisticated statistical techniques, has allowed the identification of specific genes and proteins that contribute to risk for complex human diseases.

Identifying defective genes and disease-causing gene combinations will lead to commercially viable genetics based diagnostics and therapies for human diseases. These are early stage endeavors with tremendous growth potential. Triaj offers a broad range of services related to gene discovery, ranging from general advisory and project review to large scale applied consulting projects. Triaj's biotechnology professionals are recognized international leaders in their fields, and include experts in genetics, genomics, proteomics, molecular biology, genetic statistics, clinical epidemiology, genetic epidemiology, biostatistics, bioinfomatics, diagnostics, therapeutics, and gene mapping.

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Bioinformatics: Mining for gold

Bioinformatics is a new discipline that marries the techniques of computer science, genomics, proteomics and biostatistics, to obtain exploitable information from the enormous quantities of genetic data currently being created by publicly and privately funded initiatives. Such data are derived from a number of sources, including genomic sequence, DNA polymorphism identification and gene expression experiments. Data mining, using cutting-edge computer technology combined with specialized statistical and informatics methods, is the principal means by which biomedical knowledge and commercial added-value will be obtained from the large and rapidly expanding genomic databases.

Triaj offers a broad range of services related to bioinformatics, ranging from general advisory and project review to large scale applied consulting projects. Triaj's biotechnology professionals are recognized international leaders in their fields, and include experts in genetics, genomics, proteomics, molecular biology, genetic statistics, clinical epidemiology, genetic epidemiology, biostatistics, bioinfomatics, diagnostics, therapeutics, and gene mapping. Triaj's professional staff has an unparalleled wealth of expertise in all aspects of bioinformatics, including study design, database construction and management, analysis of microarray data, and biostatistical analysis.

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Functional Genomics: Networks of Genes

Functional genomics investigates gene function in disease processes or in response to therapy. Methods to simultaneously examine the effects of thousands of genes have only recently been commercialized under the name of "gene chips" or "microarrays." This area of biotechnology is rapidly exploding, and holds enormous commercial opportunities.

The potential for using gene expression analyses to generate diagnostic or prognostic forecasts for diseases is enormous, providing significant commercial opportunities. Timing, efficacy and response to treatment can eventually be monitored using microarrays; microarray-based technologies are likely to replace many current diagnostic methods.

Triaj offers a broad range of services related to functional genomics, ranging from general consulting and project review to large scale applied consulting projects. Triaj's team of biotechnology professionals are recognized international leaders in their fields, and include experts in genetics, genomics, proteomics, molecular biology, genetic statistics, clinical epidemiology, genetic epidemiology, biostatistics, bioinfomatics, diagnostics, therapeutics, and gene mapping. Triaj's professional staff has an unparalleled wealth of expertise in all aspects of bioinformatics, including study design, database construction and management, analysis of microarray data, and biostatistical analysis.

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